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New Model Allows Testing of Hepatitis C Treatments
'This is the first efficient and consistent model system for HCV to be developed,' Martina Buck, assistant professor of medicine at the University of California, San Diego, School of Medicine, who developed the culture, said in a university news release.

Natalie Cole Says She Has Hepatitis C
NEW YORK (AP) - Grammy-winning singer Natalie Cole has been diagnosed with hepatitis C, her publicist said in a statement Wednesday. Hepatitis C is a liver disease spread through contact with infected blood. The statement said the disease was revealed

Natalie Cole says she has hepatitis C (07/17/2008)
Grammy-winning singer Natalie Cole has been diagnosed with hepatitis C, her publicist said in a statement yesterday. Hepatitis C is a liver disease spread through contact with infected blood. The statement said the disease was revealed during a routine

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Hep C and Fatty Liver Disease Linked by Enzyme
Pittsburgh researchers have found that an enzyme known to participate in fat production is elevated in those with Hepatitis C. Further exploration of this enzyme could help physicians better predict which HCV patients are at risk of developing fatty liver...

ANA773 Resumes Race Against Hepatitis C
By reducing the dosing schedule in half, Anadys Pharmaceuticals returns to their investigation of ANA773, a Toll-Like Receptor-7 agonist prodrug. Approaching the Hepatitis C virus differently from most other contenders, Phase I clinical trials evaluating the safety, tolerability and viral-load...

Popular Illegal Drug Extra Harmful with HCV
Although scores of Americans are turning to the street drug methamphetamine to keep them awake and thin, scientists have found that it worsens Hepatitis C infection in two worrisome ways....

table 5

Subclinical Hepatic Encephalopathy Impairs Daily Functioning

table  5.   SIP Scores of 38 Cirrhotic Patients at Baseline and After 3 Months

T = 0 mo T = 3 mo P* Intraclass Correlation

Psychosocial scales
  Social interactions 10 (6.3-13.7) 9.6 (6.2-13) 0.82 0.84
  Alterness 14 (7.6-20.7) 12.6 (5.5-19.7) 0.46 0.89
  Emotional behavior 8.6 (3.4-13.8) 6.9 (3.0-10.7) 0.77 0.81
  Communication 4.6 (1.1-8.2) 5.1 (0.9-9.2) 0.87 0.82
  Total psychosocial subscore 9.6 (5.9-13.2) 8.8 (5.1-12.6) 0.56 0.94
Physical scales
  Ambulation 5.8 (3.1-8.4) 5.1 (2.5-7.8) 0.69 0.88
  Mobility 5.0 (1.5-8.5) 5.2 (2.1-8.3) 0.85 0.58
  Bodycare and movement 2.9 (1.2-4.7) 2.9 (1.1-4.6) 0.99 0.88
  Total physical subscore 4.0 (2.1-5.9) 3.7 (2.1-5.4) 1.0 0.89
Independent scales
  Sleep/rest 11.4 (6.3-16.5) 9.3 (5.2-13.4) 0.56 0.83
  Work 22.9 (15.7-30.1) 21.1 (14-28.2) 0.67 0.89
  Home management 9.2 (5.6-12.7) 11.8 (7.2-16.5) 0.53 0.67
  Recreation and pastimes 14.7 (8.2-21.1) 12 (7.1-16.9) 0.88 0.67
  Eating 3.6 (2-5.2) 2.6 (1.1-4.1) 0.25 0.58
Total SIP score 8.5 (5.8-11.1) 7.9 (5.3-10.5) 0.68 0.96

NOTE. Mean scores are given; 95% confidence interval of mean between brackets.
* Wilcoxon rank sum test.

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