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Vertex recieves FDA approval for Phase III hepatitis drug
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Hepatitis E death toll hits 114
By Dennis Ojwee FOUR more people have died of Hepatitis E in Kitgum district, increasing the death toll to 114. This is out of a cumulative number of 7,331 people infected with the disease, according to district officials. The chairman of the Hepatitis

Rains to worsen Hepatitis E, says official
Gulu The start of the rainy season may worsen the spread of Hepatitis E, Gulu district disease surveillance officer Michael Cankara has said. The warning comes at a time when the disease has claimed over 106 lives and infected over 6000 in various parts

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table 3

Subclinical Hepatic Encephalopathy Impairs Daily Functioning

table  3.   SIP Scores of Cirrhotic Patients With and Without SHE

SIP Scales (No. of Items Per Scale) Reference Population (n = 594)Dagger Cirrhosis With SHE (n = 48) Cirrhosis Without SHE (n = 131) P* Internal Consistencydagger

Psychosocial scales
  Social interactions (20) 4 14.7 (11.1-18.2) 7 (5.3-8.6) <0.001 0.75
  Alertness (10) 4.7 21.3 (14.3-28.2) 8.1 (5.4-10.7) <0.001 0.81
  Emotional behavior (9) 3.9 10.9 (6.5-15.4) 5.0 (3.3-6.7) 0.01 0.67
  Communication (9) 1.0 5.9 (2.8-9) 1.5 (0.4-2.5) 0.001 0.57
  Total psychosocial subscore 13.3 (9.7-16.9) 5.7 (4.3-7.1) <0.001 0.89
Physical scales
  Ambulation (12) 3.0 7 (4.6-9.3) 3.1 (2.1-4.0) 0.002 0.53
  Mobility (10) 2.3 9.4 (5.6-13.1) 2.2 (1.2-3.2) <0.001 0.67
  Bodycare and movement (23) 1.9 5 (2.9-7.2) 1.2 (0.7-1.6) <0.001 0.68
  Total physical subscore 6.3 (4.1-8.5) 1.8 (1.2-2.4) <0.001 0.84
Independent scales
  Sleep/rest (7) 4.7 18.4 (13.5-23.4) 8.4 (6.6-10.2) <0.001 0.38
  Work (9) 7.3 24.7 (18.3-31.2) 8.7 (5.9-11.5) <0.001 0.52
  Home management (10) 4.8 14.6 (9.1-20) 5.9 (4.5-7.3) 0.001 0.54
  Recreations and pastimes (8) 5.8 23.9 (17-30.8) 9.8 (7.5-12.1) <0.001 0.60
  Eating (9) 1.0 5.1 (3.3-7) 2 (1.4-2.6) 0.007 0.20
Total SIP score 3.4 12 (9.5-14.5) 4.6 (3.7-5.5) <0.001 0.92

NOTE. Scores are minimally 0 (good performance) and maximally 100 (bad performance). Mean scores are given; 95% confidence interval of mean scores between brackets.
* Wilcoxon rank sum test.
Cronbachs  (pooled data).
Dagger Reference population: Dutch citizens.

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