Clinical Features of Hepatitis C-Infected Patients With
Persistently Normal Alanine Transaminase Levels in the Southwestern
United States
| table 2.
Biochemistry of Patients With Persistently Normal and Abnormal
ALT |
|
| No.
of Patients |
Normal ALT
|
Abnormal ALT
|
P
Value |
| N = 75 |
N = 200 |
|
| ALT value in males (U/L)
mean ± SD |
45.6 ± 13.0 |
151.8 ± 47.6 |
<.001 |
| ALT value in females (U/L)
mean ± SD |
35.3 ± 6.1 |
112.8 ± 33.5 |
<.001 |
| Iron (µg/dL) mean ± SD |
109 ± 76 |
127 ± 60 |
NS |
| TIBC (µg/dL) mean ± SD |
339 ± 80 |
358 ± 71 |
NS |
| Iron saturation (%)
mean ± SD |
32% ± 16.9% |
37% ± 6.8% |
NS |
| Ferritin (ng/mL) mean ± SD |
128 ± 92 |
224 ± 128 |
.017 |
| Bilirubin (mg/dL) mean ± SD |
1.00 ± 0.5 |
1.05 ± 0.5 |
NS |
| Albumin (g/L) mean ± SD |
3.8 ± 0.5 |
3.9 ± 0.5 |
NS |
| PT (sec) mean ± SD |
12.0 ± 1.1 |
12.7 ± 1.2 |
NS |
| RNA (copies/mL) mean ± SD |
12 × 105 ± 2.8 × 10
6 |
33 × 105 ± 8.0 × 10
6 |
.02 |
|
| Abbreviations: TIBC, total iron
binding capacity; PT, prothombin time. |
|
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