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10-Year Follow-up After Interferon-
Therapy for Chronic Hepatitis C
table 1
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| table 1.
Clinical, Serum Biochemical, Histological, and Serological Features
of Ten Patients With Chronic Hepatitis C Treated With Alpha
Interferon |
|
| No. |
Clinical
Features
|
Initial
|
Final
|
Follow-up (yr) |
Clinical Outcome |
| Resp |
Age (yr) |
Sex |
Source |
Genotype |
RNA |
ALT |
HAI |
RNA |
ALT |
HAI |
Liver RNA |
|
| 1 |
SR |
30 |
M |
IDU |
1a |
+ |
376 |
11 |
<100 |
20 |
3 |
 |
11 |
Asymptomatic |
| 2 |
SR |
27 |
M |
Tx |
2a/2b |
+ |
460 |
8 |
<100 |
52 |
3 |
|
10 |
Asymptomatic |
| 3 |
SR |
37 |
M |
IDU |
2a |
+ |
306 |
11 |
<100 |
21 |
1 |
 |
11 |
Asymptomatic |
| 4 |
SR |
40 |
M |
Tx |
3 |
+ |
272 |
11 |
<100 |
35 |
2 |
 |
10 |
Asymptomatic |
| 5 |
SR |
29 |
M |
Tx |
2a |
+ |
185 |
11 |
<100 |
23 |
0 |
 |
10 |
Asymptomatic |
| 6 |
NR |
51 |
M |
IDU |
1 |
+ |
219 |
12 |
1500 |
23 |
11 |
NA |
13 |
HCC/OLT |
| 7 |
NR |
41 |
M |
Unknown |
1b |
+ |
419 |
14 |
.18 × 106 |
181 |
12 |
NA |
6 |
Died/Stroke |
| 8 |
NR |
62 |
F |
Tx |
1b |
+ |
200 |
8 |
.049 × 106 |
248 |
16 |
+ |
11 |
Symptoms |
| 9 |
NR |
38 |
M |
Tx |
1a |
+ |
148 |
17 |
>5 × 106 |
102 |
15 |
+ |
11 |
Symptoms |
| 10 |
NR |
46 |
M |
Tx |
1b |
+ |
392 |
15 |
1.4 × 106 |
326 |
12 |
NA |
11 |
Symptoms |
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| Abbreviations: Resp, virological response;
SR, sustained response; NR, non-response; IDU, injection drug use;
Tx, transfusion; HAI, histology activity index score; HCC,
hepatocellular carcinoma; OLT, orthotopic liver transplantation;
NA, not available. |
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