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A Prospective, Community-Based Evaluation of Liver Enzymes in Individuals With Hepatitis C After Drug Use

table  3.   Correlates of HCV-Infected Individuals With Elevated ALT Values: Adjusted Odds Ratios Estimated by Multivariate Logistic Regression

Odds Ratio (95% CI)* P

Male 3.3 (2.5-4.5) <.001
Alcohol use 1.6 (1.2-2.1) <.001
Age 41 yr 1.6 (1.2-2.1) <.001
Injection drug use 0.6 (0.5-0.8) <.001
Body mass index
  20.3-22 1.5 (0.9-2.5) .087
  22.1-24.7 2.0 (1.2-3.2) .007
  >24.7 2.8 (1.6-4.8) <.001

* Odds ratio estimated with multivariate logistic regression by comparing those with normal ALT with those with elevated ALT based on 3,584 total ALT measurements. Because they were available only for a subset of participants, body mass index estimates were derived from a separate model that also included HIV infection and the other variates that are shown. Body mass index was categorized into quartiles and comparisons made versus those in the lowest quartile (<20.3). The level of association of other variates was similar in the body mass index-containing model.

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