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Vertex recieves FDA approval for Phase III hepatitis drug
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Hepatitis E death toll hits 114
By Dennis Ojwee FOUR more people have died of Hepatitis E in Kitgum district, increasing the death toll to 114. This is out of a cumulative number of 7,331 people infected with the disease, according to district officials. The chairman of the Hepatitis

Rains to worsen Hepatitis E, says official
Gulu The start of the rainy season may worsen the spread of Hepatitis E, Gulu district disease surveillance officer Michael Cankara has said. The warning comes at a time when the disease has claimed over 106 lives and infected over 6000 in various parts

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Silymarin Improves Quality of Life During Hepatitis C Treatment
Although a large-scale study concluded long-term interferon therapy to be ineffectual for Hepatitis C management, it demonstrated improvements in quality of life for participants supplementing with silymarin....

Early Hepatitis C Treatment Increases Success
Currently approved treatment for chronic Hepatitis C is about 50 percent effective. New research from Canada claims that early treatment boosts its effectiveness up to 90 percent....

Popular Blood Thinner May Reduce Liver Scarring for HCV Patients
Successful animal studies have paved the way for a human trial to determine if warfarin prevents liver damage in those with Hepatitis C....

A Prospective, Community-Based Evaluation of Liver Enzymes in Individuals With Hepatitis C After Drug Use

table  1.   Correlates of Serial ALT Values Among HCV-Infected Individuals

Number ALT Not Elevated*
% (n)
ALT Elevated <50%
Visits % (n)
ALT Elevated 50%
Visits % (n)
ALT Always
Elevated % (n)
P

Gender
  Male 789 34 (271) 22 (176) 23 (183) 20 (159)  
  Female 253 62 (157) 15 (39) 11 (28) 11 (29) .001
Age (yr)
  <41 551 37 (203) 20 (112) 23 (129) 19 (107)  
  41 491 46 (225) 21 (103) 17 (82) 17 (81) .002
Alcohol Usedagger
  Yes 665 38 (252) 22 (146) 21 (138) 19 (129)  
  No 377 47 (176) 18 (69) 19 (73) 16 (59) .012
Current IDUdagger
  Yes 629 44 (279) 20 (128) 21 (132) 14 (90)  
  No 413 36 (149) 21 (87) 19 (79) 23 (98) .001
HIV Negative 568 41.5 (236) 20.6 (117) 19.9 (113) 18 (102)  
HIV Positive
  CD4 >500 94 42.5 (40) 17.0 (16) 23.4 (22) 17.0 (16)  
  CD4 200-499  211 37.9 (80) 21.3 (45) 21.8 (46) 19.0 (40)  
  CD4 0-199  159 43.4 (69) 22.6 (36) 17.0 (27) 17.0 (27) >.10

Abbreviations: IDU, injection drug use; CD4 count expressed in cells/mL.
* ALT values drawn at intervals 6 mo. All individuals had at least 2, but no more than 5, measurements.
dagger Alcohol drinker defined as regular alcohol intake in 6 mo before visit.
dagger Current IDU defined as use of injection drugs in 6 mo before visit.

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