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UNITED STATES: FDA Approves Hepatitis B Viral DNA Test
The first hepatitis B virus (HBV) nucleic acid test to measure the amount of viral DNA in a patient's blood has won Food and Drug Administration approval. 'The COBAS TaqMan HBV Test extracts and then amplifies sections of viral DNA from human plasma or

Toll rises to 121 in Uganda hepatitis epidemic
A hepatitis E epidemic has killed 121 people in northern Uganda, where it erupted in October last year, a health ministry official said Thursday. A diagram showing the hepatitis C virus © AFP/File KAMPALA (AFP) - The outbreak has mainly affected

Roche Molecular Diagnostics Wins FDA OK for Hepatitis B Test
A hepatitis B viral load test, developed by Roche Molecular Diagnostics in Pleasanton, was approved by the Food and Drug Administration.

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HCV Genotype 1 Viral Loads Decline
A six-month follow-up to Intercell's Phase II trial of their Hepatitis C vaccine with a topical toll-like receptor agonist showed a significant reduction in viral load. While data from two weeks after the vaccination series showed promise, participants with Hepatitis...

Former Anti-Itch Drug Useful Against Hep C
California scientists have found that an old antihistamine drastically reduces Hepatitis C viral replication....

Hep C Treatment: Comparing the Pegylated Interferons
Learn about the facts on pegylated interferon alfa-2a and pegylated interferon alfa-2b, the standard treatment for chronic Hepatitis C. Comparing and contrasting the pegylated interferons may help better explain a physician’s preference or indifference between the two when treating their...

Frequency and Nature of the Variant Syndromes of Autoimmune Liver Disease

table  5.   Features Associated With Corticosteroid Responses in the Variant Syndromes
Features Corticosteroid Responses
Remission (n = 11) Treatment Failure (n = 4) Poor Response (n = 10)
AST (reference value, 31 U/L) 699 ± 203 520 ± 309 372 ± 162
Bilirubin (reference value, 1.1 mg/dL) 4.9 ± 1.4 5.5 ± 3.1 5.7 ± 2.6
Alkaline phosphatase (reference value, 309 U/L) 276 ± 53 881 ± 339 786 ± 174
Alkaline phosphatase 2× reference value  0 (0)* 2 (50) 5 (50)
 -Globulin (reference value, 0.7-1.7 g/dL) 3.6 ± 0.2Dagger 2.9 ± 0.5 2.7 ± 0.3
 -Globulin 2× reference value  6 (54) 1/3 (33) 3 (30)
Immunoglobulin G (reference value, 700-1500 mg/dL) 3134 ± 314§ 2998 ± 713 2596 ± 357
Immunoglobulin G 2× reference value  6 (54) 2 (50) 4 (40)
SMA 1:40 10 (91) 3 (75) 6 (67)
ANA 1:40  5 (45) 3 (75) 6 (60)
DR4+  5 (45) 2 (50) 4 (40)
Autoimmune score 16 ± 1 16 ± 2 16 ± 1
Aggregate scores >15  5 (45) 2 (50) 5 (50)
NOTE. Numbers in parentheses are percentages.
Abbreviation: AST, serum aspartate aminotransferase level.
Significantly different from those without the response at levels of *,Dagger P = .001, P = .004, and §P = .04.

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